Inhibitors | Comment | Organism | Structure |
---|---|---|---|
KYP-2047 | selective inhibitor, i.e (2S)-1[(2S)-1-(1-oxo-4-phenylbutyl)-2-pyrrolidinylcarbonyl]-2-pyrrolidinecarbonitrile | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
corpus luteum | - |
Mus musculus | - |
luteal cell | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
succinyl-Gly-L-Pro-L-Leu-Gly-L-Pro-7-amido-4-methylcoumarin + H2O | - |
Mus musculus | succinyl-Gly-L-Pro-L-Leu-Gly-L-Pro + 7-amino-4-methylcoumarin | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 80000, SDS-PAGE | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
PEP | - |
Mus musculus |
POP | - |
Mus musculus |
PREP | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | enzyme overexpression increases progesterone secretion, increases ERK1/2 phosphorylation and increases the expression of steroidogenic factor 1. The enzyme regulates progesterone secretion by stimulating the expression of CYP11A, 3beta-hydroxysteroid dehydrogenase, and steroidogenic acute regulatory protein in luteal cells | Mus musculus |